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Synergy of Combined tPA-Edaravone Therapy in Experimental Thrombotic Stroke

Edaravone, a potent antioxidant, may improve thrombolytic therapy because it benefits ischemic stroke patients on its own and mitigates adverse effects of tissue plasminogen activator (tPA) in preclinical models. However, whether the combined tPA-edaravone therapy is more effective in reducing infar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sun, Yu-Yo, Morozov, Yury M., Yang, Dianer, Li, Yikun, Dunn, R. Scott, Rakic, Pasko, Chan, Pak H., Abe, Koji, Lindquist, Diana M., Kuan, Chia-Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049665/
https://ncbi.nlm.nih.gov/pubmed/24911517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098807
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