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Synergy of Combined tPA-Edaravone Therapy in Experimental Thrombotic Stroke

Edaravone, a potent antioxidant, may improve thrombolytic therapy because it benefits ischemic stroke patients on its own and mitigates adverse effects of tissue plasminogen activator (tPA) in preclinical models. However, whether the combined tPA-edaravone therapy is more effective in reducing infar...

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Autori principali: Sun, Yu-Yo, Morozov, Yury M., Yang, Dianer, Li, Yikun, Dunn, R. Scott, Rakic, Pasko, Chan, Pak H., Abe, Koji, Lindquist, Diana M., Kuan, Chia-Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049665/
https://ncbi.nlm.nih.gov/pubmed/24911517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098807
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