Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

A major challenge in vaccinology is to prospectively determine vaccine efficacy. Here we have used a systems biology approach to identify early gene ‘signatures’ that predicted immune responses in humans vaccinated with yellow fever vaccine YF-17D. Vaccination induced genes that regulate virus innat...

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Detalhes bibliográficos
Main Authors: Querec, Troy D, Akondy, Rama S, Lee, Eva K, Cao, Weiping, Nakaya, Helder I, Teuwen, Dirk, Pirani, Ali, Gernert, Kim, Deng, Jiusheng, Marzolf, Bruz, Kennedy, Kathleen, Wu, Haiyan, Bennouna, Soumaya, Oluoch, Herold, Miller, Joseph, Vencio, Ricardo Z, Mulligan, Mark, Aderem, Alan, Ahmed, Rafi, Pulendran, Bali
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049462/
https://ncbi.nlm.nih.gov/pubmed/19029902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1688
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