Sunitinib significantly suppresses the proliferation, migration, apoptosis resistance, tumor angiogenesis and growth of triple-negative breast cancers but increases breast cancer stem cells

The majority of triple-negative breast cancers (TNBCs) are basal-like breast cancers. However there is no reported study on anti-tumor effects of sunitinib in xenografts of basal-like TNBC (MDA-MB-468) cells. In the present study, MDA-MB-231, MDA-MB-468, MCF-7 cells were cultured using RPMI 1640 med...

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Hlavní autoři: Chinchar, Edmund, Makey, Kristina L, Gibson, John, Chen, Fang, Cole, Shelby A, Megason, Gail C, Vijayakumar, Srinivassan, Miele, Lucio, Gu, Jian-Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049452/
https://ncbi.nlm.nih.gov/pubmed/24914410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-6-12
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