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Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines
While the past decade has seen great progress in mapping loci for common diseases, studying how these risk alleles lead to pathology remains a challenge. Age-related macular degeneration (AMD) affects 9 million older Americans, and is characterized by the loss of the retinal pigment epithelium (RPE)...
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| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4049304/ https://ncbi.nlm.nih.gov/pubmed/24497574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu053 |
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