Specific antioxidant compounds differentially modulate cytotoxic activity of doxorubicin and cisplatin: in vitro and in vivo study

AIM: To use the antioxidant compounds (sodium selenite, selenomethionine, D-pantethine) for modulation of cytotoxic effect of doxorubicin and cisplatin toward wild type and drug-resistant mutants of several human tumor cells. Similar treatments were applied in vivo toward adult male Wistar rats. MET...

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Detalhes bibliográficos
Main Authors: Panchuk, Rostyslav, Skorokhyd, Nadia, Chumak, Vira, Lehka, Lilya, Omelyanchik, Sofya, Gurinovich, Valery, Moiseenok, Andrey, Heffeter, Petra, Berger, Walter, Stoika, Rostyslav
Formato: Artigo
Idioma:Inglês
Publicado em: Croatian Medical Schools 2014
Assuntos:
Central and Eastern European Biomedical Bridges
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049213/
https://ncbi.nlm.nih.gov/pubmed/24891279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3325/cmj.2014.55.206
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