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The TWEAK-Fn14 dyad is involved in age-associated pathological changes in skeletal muscle

Progressive loss of skeletal muscle mass and strength (sarcopenia) is a major clinical problem in the elderly. Recently, proinflammatory cytokine TWEAK and its receptor Fn14 were identified as key mediators of muscle wasting in various catabolic states. However, the role of the TWEAK-Fn14 pathway in...

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Autores principales: Tajrishi, Marjan M., Sato, Shuichi, Shin, Jonghyun, Zheng, Timothy S., Burkly, Linda C., Kumar, Ashok
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049113/
https://ncbi.nlm.nih.gov/pubmed/24680686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.03.084
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