Dietary Pyridoxine Controls Efficacy of Vitamin B(6)-Auxotrophic Tuberculosis Vaccine Bacillus Calmette-Guérin ΔureC::hly Δpdx1 in Mice

The only tuberculosis (TB) vaccine in use today, bacillus Calmette-Guérin (BCG), provides insufficient protection and can cause adverse events in immunocompromised individuals, such as BCGosis in HIV(+) newborns. We previously reported improved preclinical efficacy and safety of the recombinant vacc...

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Detalhes bibliográficos
Main Authors: Gengenbacher, Martin, Vogelzang, Alexis, Schuerer, Stefanie, Lazar, Doris, Kaiser, Peggy, Kaufmann, Stefan H. E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049106/
https://ncbi.nlm.nih.gov/pubmed/24895310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01262-14
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