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Reduced vesicular storage of catecholamines causes progressive degeneration in the locus ceruleus

Parkinson’s disease (PD) is the most common neurodegenerative motor disease. Pathologically, PD is characterized by Lewy body deposition and subsequent death of dopamine neurons in the substantia nigra pars compacta. PD also consistently features degeneration of the locus ceruleus, the main source o...

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Detalhes bibliográficos
Main Authors: Taylor, Tonya N., Alter, Shawn P., Wang, Minzheng, Goldstein, David S., Miller, Gary W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049095/
https://ncbi.nlm.nih.gov/pubmed/24025942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.08.033
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