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Transient α-helices in the disordered RPEL motifs of the serum response factor coactivator MKL1
The megakaryoblastic leukemia 1 (MKL1) protein functions as a transcriptional coactivator of the serum response factor. MKL1 has three RPEL motifs (RPEL1, RPEL2, and RPEL3) in its N-terminal region. MKL1 binds to monomeric G-actin through RPEL motifs, and the dissociation of MKL1 from G-actin promot...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048911/ https://ncbi.nlm.nih.gov/pubmed/24909411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05224 |
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