Synaptic localisation of SRF coactivators, MKL1 and MKL2, and their role in dendritic spine morphology

The megakaryoblastic leukaemia (MKL) family are serum response factor (SRF) coactivators, which are highly expressed in the brain. Accordingly, MKL plays important roles in dendritic morphology, neuronal migration, and brain development. Further, nucleotide substitutions in the MKL1 and MKL2 genes a...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kaneda, Marisa, Sakagami, Hiroyuki, Hida, Yamato, Ohtsuka, Toshihisa, Satou, Natsumi, Ishibashi, Yuta, Fukuchi, Mamoru, Krysiak, Anna, Ishikawa, Mitsuru, Ihara, Daisuke, Kalita, Katarzyna, Tabuchi, Akiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768758/
https://ncbi.nlm.nih.gov/pubmed/29335431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18905-7
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