Multifunctional Aptamer-miRNA Conjugates for Targeted Cancer Therapy

While microRNAs (miRNAs) clearly regulate multiple pathways integral to disease development and progression, the lack of safe and reliable means for specific delivery of miRNAs to target tissues represents a major obstacle to their broad therapeutic application. Our objective was to explore the use...

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Detalhes bibliográficos
Main Authors: Esposito, Carla L, Cerchia, Laura, Catuogno, Silvia, De Vita, Gennaro, Dassie, Justin P, Santamaria, Gianluca, Swiderski, Piotr, Condorelli, Gerolama, Giangrande, Paloma H, de Franciscis, Vittorio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048903/
https://ncbi.nlm.nih.gov/pubmed/24441398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.5
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