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RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent Transcription

RNAi based strategies to induce gene silencing are commonly employed in numerous model organisms but have not been extensively used in zebrafish. We found that introduction of transgenes containing convergent transcription units in zebrafish embryos induced stable transcriptional gene silencing (TGS...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Andrews, Omozusi E., Cha, Diana J., Wei, Chunyao, Patton, James G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048883/
https://ncbi.nlm.nih.gov/pubmed/24909225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05222
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