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Initial Characterization of Fom3 from Streptomyces wedmorensis: The Methyltransferase in Fosfomycin Biosynthesis

Fosfomycin is a broad-spectrum antibiotic that is useful against multi-drug resistant bacteria. Although its biosynthesis was first studied over 40 years ago, characterization of the penultimate methyl transfer reaction has eluded investigators. The enzyme believed to catalyze this reaction, Fom3, h...

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Hlavní autoři: Allen, Kylie D., Wang, Susan C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048823/
https://ncbi.nlm.nih.gov/pubmed/24370735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2013.12.004
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