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Targeting antigens through blood dendritic cell antigen 2 (BDCA2) on plasmacytoid dendritic cells promotes immunologic tolerance()

The C-type lectin receptor blood dendritic cell antigen 2 (BDCA2) is expressed exclusively on human plasmacytoid dendritic cells (pDCs) and plays a role in Ag capture, internalization and presentation to T cells. We used transgenic mice that express human BDCA2 and anti-BDCA2 mAbs to deliver Ags dir...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Chappell, Craig P., Giltiay, Natalia V., Draves, Kevin E., Chen, ChangHung, Hayden-Ledbetter, Martha S., Shlomchik, Mark J., Kaplan, Daniel H., Clark, Edward A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048786/
https://ncbi.nlm.nih.gov/pubmed/24829416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303259
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