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Co-regulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers
Transcription factors (TFs) preferentially bind sites contained in regions of computationally predicted high nucleosomal occupancy, suggesting that nucleosomes are gatekeepers of TF binding sites. However, because of their complexity mammalian genomes contain millions of randomly occurring, unbound...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048654/ https://ncbi.nlm.nih.gov/pubmed/24813947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.04.006 |
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