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A first exon termination checkpoint preferentially suppresses extragenic transcription
Interactions between the splicing machinery and RNA Polymerase II (RNA Pol II) increase protein-coding gene transcription. Similarly, exons and splicing signals of enhancer-generated lncRNAs (elncRNAs) augment enhancer activity. However, elncRNAs are inefficiently spliced, suggesting that compared t...
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| 出版年: | Nat Struct Mol Biol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610630/ https://ncbi.nlm.nih.gov/pubmed/33767452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-021-00572-y |
| タグ: |
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