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Site-Identification by Ligand Competitive Saturation (SILCS) Assisted Pharmacophore Modeling

Database screening using receptor-based pharmacophores is a computer-aided drug design technique that uses the structure of the target molecule (i.e. protein) to identify novel ligands that may bind to the target. Typically receptor-based pharmacophore modeling methods only consider a single or limi...

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Autors principals: Yu, Wenbo, Lakkaraju, Sirish Kaushik, Raman, E. Prabhu, MacKerell, Alexander D.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048638/
https://ncbi.nlm.nih.gov/pubmed/24610239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-014-9728-0
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