Nitrosative Stress Induces Peroxiredoxin 1 Ubiquitination During Ischemic Insult via E6AP Activation in Endothelial Cells Both In Vitro and In Vivo

Aims: Although there is accumulating evidence that increased formation of reactive nitrogen species in cerebral vasculature contributes to the progression of ischemic damage, but the underlying molecular mechanisms remain elusive. Peroxiredoxin 1 (Prx1) can initiate the antioxidant response by scave...

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Autores principales: Tao, Rong-Rong, Wang, Huan, Hong, Ling-Juan, Huang, Ji-Yun, Lu, Ying-Mei, Liao, Mei-Hua, Ye, Wei-Feng, Lu, Nan-Nan, Zhu, Dan-Yan, Huang, Qian, Fukunaga, Kohji, Lou, Yi-Jia, Shoji, Ikuo, Wilcox, Christopher Stuart, Lai, En-Yin, Han, Feng
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2014
Materias:
Original Research Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048580/
https://ncbi.nlm.nih.gov/pubmed/24295341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5381
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