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Genetic distance as an alternative to physical distance for definition of gene units in association studies

BACKGROUND: Some association studies, as the implemented in VEGAS, ALIGATOR, i-GSEA4GWAS, GSA-SNP and other software tools, use genes as the unit of analysis. These genes include the coding sequence plus flanking sequences. Polymorphisms in the flanking sequences are of interest because they involve...

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Detalhes bibliográficos
Main Authors: Rodriguez-Fontenla, Cristina, Calaza, Manuel, Gonzalez, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048458/
https://ncbi.nlm.nih.gov/pubmed/24884992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-408
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