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Genetic distance as an alternative to physical distance for definition of gene units in association studies

BACKGROUND: Some association studies, as the implemented in VEGAS, ALIGATOR, i-GSEA4GWAS, GSA-SNP and other software tools, use genes as the unit of analysis. These genes include the coding sequence plus flanking sequences. Polymorphisms in the flanking sequences are of interest because they involve...

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Bibliografske podrobnosti
Main Authors: Rodriguez-Fontenla, Cristina, Calaza, Manuel, Gonzalez, Antonio
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048458/
https://ncbi.nlm.nih.gov/pubmed/24884992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-408
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