Archaeal Tuc1/Ncs6 Homolog Required for Wobble Uridine tRNA Thiolation Is Associated with Ubiquitin-Proteasome, Translation, and RNA Processing System Homologs

While cytoplasmic tRNA 2-thiolation protein 1 (Tuc1/Ncs6) and ubiquitin-related modifier-1 (Urm1) are important in the 2-thiolation of 5-methoxycarbonylmethyl-2-thiouridine (mcm(5)s(2)U) at wobble uridines of tRNAs in eukaryotes, the biocatalytic roles and properties of Ncs6/Tuc1 and its homologs ar...

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Hauptverfasser: Chavarria, Nikita E., Hwang, Sungmin, Cao, Shiyun, Fu, Xian, Holman, Mary, Elbanna, Dina, Rodriguez, Suzanne, Arrington, Deanna, Englert, Markus, Uthandi, Sivakumar, Söll, Dieter, Maupin-Furlow, Julie A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048286/
https://ncbi.nlm.nih.gov/pubmed/24906001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099104
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