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HKH40A downregulates GRP78/BiP expression in cancer cells
HKH40A, the 8-methoxy analog of WMC79, is a synthetic agent with promising in vitro and in vivo antitumor activity, especially against solid tumors. However, molecular mechanisms underlying its antitumor effects are poorly understood. Here, we report that HKH40A markedly reduces the level of GRP78/B...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047900/ https://ncbi.nlm.nih.gov/pubmed/24853418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.203 |
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