Elf3 drives β-catenin transactivation and associates with poor prognosis in colorectal cancer

Aberrant regulation of the Wnt/β-catenin pathway plays important roles in colorectal carcinogenesis, with over 90% of cases of sporadic colon cancer featuring β-catenin accumulation. While ubiquitination-mediated degradation is widely accepted as a major route for β-catenin protein turnover, little...

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Detalhes bibliográficos
Main Authors: Wang, J-L, Chen, Z-F, Chen, H-M, Wang, M-Y, Kong, X, Wang, Y-C, Sun, T-T, Hong, J, Zou, W, Xu, J, Fang, J-Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047871/
https://ncbi.nlm.nih.gov/pubmed/24874735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.206
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