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Tissue-engineered cartilage with inducible and tunable immunomodulatory properties

The pathogenesis of osteoarthritis is mediated in part by inflammatory cytokines including interleukin-1 (IL-1), which promote degradation of articular cartilage and prevent human mesenchymal stem cell (MSC) chondrogenesis. In this study, we combined gene therapy and functional tissue engineering to...

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Main Authors: Glass, Katherine A., Link, Jarrett M., Brunger, Jonathan M., Moutos, Franklin T., Gersbach, Charles A., Guilak, Farshid
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047672/
https://ncbi.nlm.nih.gov/pubmed/24767790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.03.073
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