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Tissue-engineered cartilage with inducible and tunable immunomodulatory properties
The pathogenesis of osteoarthritis is mediated in part by inflammatory cytokines including interleukin-1 (IL-1), which promote degradation of articular cartilage and prevent human mesenchymal stem cell (MSC) chondrogenesis. In this study, we combined gene therapy and functional tissue engineering to...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047672/ https://ncbi.nlm.nih.gov/pubmed/24767790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.03.073 |
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