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T-cell and B-cell signaling biomarkers and treatment targets in lupus

PURPOSE OF REVIEW: Systemic lupus erythematosus is characterized by the production of antinuclear autoantibodies and dysfunction of T-cells, B-cells, and dendritic cells. Here, we review newly recognized genetic factors and mechanisms that underlie abnormal intracellular signal processing and interc...

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Détails bibliographiques
Auteurs principaux: Perl, Andras, Fernandez, David R., Telarico, Tiffany, Doherty, Edward, Francis, Lisa, Phillips, Paul E.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047522/
https://ncbi.nlm.nih.gov/pubmed/19550330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BOR.0b013e32832e977c
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