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N-Glycan Remodeling on Glucagon Receptor Is an Effector of Nutrient Sensing by the Hexosamine Biosynthesis Pathway

Glucose homeostasis in mammals is dependent on the opposing actions of insulin and glucagon. The Golgi N-acetylglucosaminyltransferases encoded by Mgat1, Mgat2, Mgat4a/b/c, and Mgat5 modify the N-glycans on receptors and solute transporter, possibly adapting activities in response to the metabolic e...

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Detaylı Bibliyografya
Asıl Yazarlar: Johswich, Anita, Longuet, Christine, Pawling, Judy, Rahman, Anas Abdel, Ryczko, Michael, Drucker, Daniel J., Dennis, James W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047366/
https://ncbi.nlm.nih.gov/pubmed/24742675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563734
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