Yin Yang-1 suppresses invasion and metastasis of pancreatic ductal adenocarcinoma by downregulating MMP10 in a MUC4/ErbB2/p38/MEF2C-dependent mechanism

BACKGROUND: Increasing evidence indicates an important role of transcription factor Yin Yang-1 (YY1) in human tumorigenesis. However, its function in cancer remains controversial and the relevance of YY1 to pancreatic ductal adenocarcinoma (PDAC) remains to be clarified. METHODS: In this study, we d...

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Detalhes bibliográficos
Main Authors: Zhang, Jing-Jing, Zhu, Yi, Xie, Kun-Ling, Peng, Yun-Peng, Tao, Jin-Qiu, Tang, Jie, Li, Zheng, Xu, Ze-Kuan, Dai, Cun-Cai, Qian, Zhu-Yin, Jiang, Kui-Rong, Wu, Jun-Li, Gao, Wen-Tao, Du, Qing, Miao, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047260/
https://ncbi.nlm.nih.gov/pubmed/24884523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-130
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