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Yin Yang-1 increases apoptosis through Bax activation in pancreatic cancer cells
The transcriptional regulator Yin Yang-1 (YY1) is a tumor suppressor known to be overexpressed in pancreatic cancer. We found that overexpression of YY1 promoted apoptosis and increased the expression and mitochondrial localization of the pro-apoptotic Bax protein in pancreatic cancer cell lines. Lu...
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| 發表在: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Impact Journals LLC
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053741/ https://ncbi.nlm.nih.gov/pubmed/27074573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8654 |
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