Methylation and Gene Expression Responses to Ethanol Feeding and Betaine Supplementation in the Cystathionine Beta Synthase-Deficient Mouse

BACKGROUND: Alcoholic steatohepatitis (ASH) is caused in part by the effects of ethanol on hepatic methionine metabolism. METHODS: To investigate the phenotypic and epigenetic consequences of altered methionine metabolism in this disease, we studied the effects of 4-wk intragastric ethanol feeding w...

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Bibliografiske detaljer
Main Authors: Medici, Valentina, Schroeder, Diane I., Woods, Rima, LaSalle, Janine M., Geng, Yongzhi, Shibata, Noreene M., Peerson, Janet, Hodzic, Emir, Dayal, Sanjana, Tsukamoto, Hidekazu, Kharbanda, Kusum K., Tillman, Brittany, French, Samuel W., Halsted, Charles H.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047166/
https://ncbi.nlm.nih.gov/pubmed/24730561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12405
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