Phase II Trial of Bortezomib Alone or in Combination with Irinotecan in Patients with Adenocarcinoma of the Gastroesophageal Junction or Stomach

PURPOSE: To determine the effectiveness of bortezomib plus irinotecan and bortezomib alone in patients with advanced gastroesophageal junction (GEJ) and gastric adenocarcinoma. We also sought to explore the effect of these therapeutics on tumor and normal gene expression in vivo. METHODS: Forty-one...

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Main Authors: Ocean, Allyson J., Christos, Paul, Sparano, Joseph A., Shah, Manish A., Yantiss, Rhonda K., Cheng, Jonathan, Lin, Juan, Papetti, Michael, Matulich, Dan, Schnoll-Sussman, Felice, Besanceney-Webler, Christen, Xiang, Jenny, Ward, Maureen, Dilts, Kaili Temple, Keresztes, Roger, Holloway, Shannon, Chen, Eric X., Wright, John J., Lane, Maureen E.
格式: Artigo
語言:Inglês
出版: 2014
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047141/
https://ncbi.nlm.nih.gov/pubmed/24526575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-014-0070-0
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