Tumor Suppressor DYRK1A Effects on Proliferation and Chemoresistance of AML Cells by Downregulating c-Myc

Acute myeloid leukemia (AML), caused by abnormal proliferation and accumulation of hematopoietic progenitor cells, is one of the most common malignancies in adults. We reported here DYRK1A expression level was reduced in the bone marrow of adult AML patients, comparing to normal controls. Overexpres...

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Detalhes bibliográficos
Main Authors: Liu, Qiang, Liu, Na, Zang, Shaolei, Liu, Heng, Wang, Pin, Ji, Chunyan, Sun, Xiulian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047119/
https://ncbi.nlm.nih.gov/pubmed/24901999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098853
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