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Multiple Mineralocorticoid Response Elements Localized in Different Introns Regulate Intermediate Conductance K(+) (Kcnn4) Channel Expression in the Rat Distal Colon

An elevated plasma aldosterone and an increased expression of the intermediate conductance K(+) (IK/Kcnn4) channels are linked in colon. This observation suggests that the expression of Kcnn4 gene is controlled through the action of aldosterone on its cognate receptor (i.e., mineralocorticoid recept...

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Detalhes bibliográficos
Main Authors: O’Hara, Bryan, de la Rosa, Diego Alvarez, Rajendran, Vazhaikkurichi M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047071/
https://ncbi.nlm.nih.gov/pubmed/24901797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098695
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