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Parallel intermediate conductance K(+) and Cl(−) channel activity mediates electroneutral K(+) exit across basolateral membranes in rat distal colon

Transepithelial K(+) absorption requires apical K(+) uptake and basolateral K(+) exit. In the colon, apical H(+)-K(+)-ATPase mediates cellular K(+) uptake, and it has been suggested that electroneutral basolateral K(+) exit reflects K(+)-Cl(−) cotransporter-1 (KCC1) operating in parallel with K(+) a...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Rehman, Shabina, Narayanan, Karthikeyan, Nickerson, Andrew J., Coon, Steven D., Hoque, Kazi Mirajul, Sandle, Geoffrey I., Rajendran, Vazhaikkurichi M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500264/
https://ncbi.nlm.nih.gov/pubmed/32567323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00011.2020
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