Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia

In the present study, an integrated hierarchical approach was applied to: (1) identify pathways associated with susceptibility to schizophrenia; (2) detect genes that may be potentially affected in these pathways since they contain an associated polymorphism; and (3) annotate the functional conseque...

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Hlavní autoři: Juraeva, Dilafruz, Haenisch, Britta, Zapatka, Marc, Frank, Josef, Witt, Stephanie H., Mühleisen, Thomas W., Treutlein, Jens, Strohmaier, Jana, Meier, Sandra, Degenhardt, Franziska, Giegling, Ina, Ripke, Stephan, Leber, Markus, Lange, Christoph, Schulze, Thomas G., Mössner, Rainald, Nenadic, Igor, Sauer, Heinrich, Rujescu, Dan, Maier, Wolfgang, Børglum, Anders, Ophoff, Roel, Cichon, Sven, Nöthen, Markus M., Rietschel, Marcella, Mattheisen, Manuel, Brors, Benedikt
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046913/
https://ncbi.nlm.nih.gov/pubmed/24901509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004345
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