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Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia

In the present study, an integrated hierarchical approach was applied to: (1) identify pathways associated with susceptibility to schizophrenia; (2) detect genes that may be potentially affected in these pathways since they contain an associated polymorphism; and (3) annotate the functional conseque...

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Detalhes bibliográficos
Main Authors: Juraeva, Dilafruz, Haenisch, Britta, Zapatka, Marc, Frank, Josef, Witt, Stephanie H., Mühleisen, Thomas W., Treutlein, Jens, Strohmaier, Jana, Meier, Sandra, Degenhardt, Franziska, Giegling, Ina, Ripke, Stephan, Leber, Markus, Lange, Christoph, Schulze, Thomas G., Mössner, Rainald, Nenadic, Igor, Sauer, Heinrich, Rujescu, Dan, Maier, Wolfgang, Børglum, Anders, Ophoff, Roel, Cichon, Sven, Nöthen, Markus M., Rietschel, Marcella, Mattheisen, Manuel, Brors, Benedikt
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046913/
https://ncbi.nlm.nih.gov/pubmed/24901509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004345
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