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Buffed energy landscapes: Another solution to the kinetic paradoxes of protein folding

The energy landscapes of proteins have evolved to be different from most random heteropolymers. Many studies have concluded that evolutionary selection for rapid and reliable folding to a given structure that is stable at biological temperatures leads to energy landscapes having a single dominant ba...

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Autori principali: Plotkin, Steven S., Wolynes, Peter G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC404690/
https://ncbi.nlm.nih.gov/pubmed/12677002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0330720100
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