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Buffed energy landscapes: Another solution to the kinetic paradoxes of protein folding

The energy landscapes of proteins have evolved to be different from most random heteropolymers. Many studies have concluded that evolutionary selection for rapid and reliable folding to a given structure that is stable at biological temperatures leads to energy landscapes having a single dominant ba...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Plotkin, Steven S., Wolynes, Peter G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC404690/
https://ncbi.nlm.nih.gov/pubmed/12677002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0330720100
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