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Specific mutations in the ligand binding domain selectively abolish the silencing function of human thyroid hormone receptor beta.

Although most nuclear hormone receptors are ligand-dependent transcriptional activators, certain members of this superfamily, such as thyroid hormone receptor (TR) and retinoic acid receptor (RAR), are involved in transcriptional repression. The silencing function of these receptors has been localiz...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Nawaz, Z, Tsai, M J, O'Malley, B W
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1995
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40468/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524830/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.25.11691
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