Specific mutations in the ligand binding domain selectively abolish the silencing function of human thyroid hormone receptor beta.
Although most nuclear hormone receptors are ligand-dependent transcriptional activators, certain members of this superfamily, such as thyroid hormone receptor (TR) and retinoic acid receptor (RAR), are involved in transcriptional repression. The silencing function of these receptors has been localiz...
Saved in:
| Published in: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1995
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40468/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524830/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.25.11691 |
| Tags: |
No Tags, Be the first to tag this record!
|