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Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

Multidrug ATP binding cassette (ABC) exporters are ubiquitous ABC transporters that extrude cytotoxic molecules across cell membranes. Despite recent progress in structure determination of these transporters, the conformational motion that transduces the energy of ATP hydrolysis to the work of subst...

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Detalhes bibliográficos
Main Authors: Mishra, Smriti, Verhalen, Brandy, Stein, Richard A, Wen, Po-Chao, Tajkhorshid, Emad, Mchaourab, Hassane S
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046567/
https://ncbi.nlm.nih.gov/pubmed/24837547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02740
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