Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

Multidrug ATP binding cassette (ABC) exporters are ubiquitous ABC transporters that extrude cytotoxic molecules across cell membranes. Despite recent progress in structure determination of these transporters, the conformational motion that transduces the energy of ATP hydrolysis to the work of subst...

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Bibliographische Detailangaben
Hauptverfasser: Mishra, Smriti, Verhalen, Brandy, Stein, Richard A, Wen, Po-Chao, Tajkhorshid, Emad, Mchaourab, Hassane S
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2014
Schlagworte:
Biochemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046567/
https://ncbi.nlm.nih.gov/pubmed/24837547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02740
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