Loading...

On the Origin of Large Flexibility of P-glycoprotein in the Inward-facing State

P-glycoprotein (Pgp) is one of the most biomedically relevant transporters in the ATP binding cassette (ABC) superfamily due to its involvement in developing multidrug resistance in cancer cells. Employing molecular dynamics simulations and double electron-electron resonance spectroscopy, we have in...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Wen, Po-Chao, Verhalen, Brandy, Wilkens, Stephan, Mchaourab, Hassane S., Tajkhorshid, Emad
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696692/
https://ncbi.nlm.nih.gov/pubmed/23658020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.450114
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!