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Combinatorial effects of malaria season, iron deficiency, and inflammation determine plasma hepcidin concentration in African children

Hepcidin is the master regulatory hormone that governs iron homeostasis and has a role in innate immunity. Although hepcidin has been studied extensively in model systems, there is less information on hepcidin regulation in global health contexts where iron deficiency (ID), anemia, and high infectio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Atkinson, Sarah H., Armitage, Andrew E., Khandwala, Shivani, Mwangi, Tabitha W., Uyoga, Sophie, Bejon, Philip A., Williams, Thomas N., Prentice, Andrew M., Drakesmith, Hal
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046425/
https://ncbi.nlm.nih.gov/pubmed/24596418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-533000
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