Combinatorial effects of malaria season, iron deficiency, and inflammation determine plasma hepcidin concentration in African children

Hepcidin is the master regulatory hormone that governs iron homeostasis and has a role in innate immunity. Although hepcidin has been studied extensively in model systems, there is less information on hepcidin regulation in global health contexts where iron deficiency (ID), anemia, and high infectio...

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Autores principales: Atkinson, Sarah H., Armitage, Andrew E., Khandwala, Shivani, Mwangi, Tabitha W., Uyoga, Sophie, Bejon, Philip A., Williams, Thomas N., Prentice, Andrew M., Drakesmith, Hal
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2014
Materias:
Plenary Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046425/
https://ncbi.nlm.nih.gov/pubmed/24596418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-533000
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