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Combinatorial effects of malaria season, iron deficiency, and inflammation determine plasma hepcidin concentration in African children

Hepcidin is the master regulatory hormone that governs iron homeostasis and has a role in innate immunity. Although hepcidin has been studied extensively in model systems, there is less information on hepcidin regulation in global health contexts where iron deficiency (ID), anemia, and high infectio...

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Detalhes bibliográficos
Main Authors: Atkinson, Sarah H., Armitage, Andrew E., Khandwala, Shivani, Mwangi, Tabitha W., Uyoga, Sophie, Bejon, Philip A., Williams, Thomas N., Prentice, Andrew M., Drakesmith, Hal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046425/
https://ncbi.nlm.nih.gov/pubmed/24596418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-533000
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