A highly active decarboxylating dehydrogenase with rationally inverted coenzyme specificity.
The isocitrate dehydrogenase of Escherichia coli, which lacks the Rossmann fold common to other dehydrogenases, displays a 7000-fold preference for NADP over NAD (calculated as the ratio of kcat/Km). Guided by x-ray crystal structures and molecular modeling, site-directed mutagenesis has been used t...
-д хадгалсан:
| -д хэвлэсэн: | Proc Natl Acad Sci U S A |
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| Үндсэн зохиолчид: | , , |
| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
National Academy of Sciences
1995
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| Нөхцлүүд: | |
| Онлайн хандалт: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40463/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524825/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.25.11666 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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