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Distinct molecular targets including SLO-1 and gap junctions are engaged across a continuum of ethanol concentrations in Caenorhabditis elegans

Ethanol (alcohol) interacts with diverse molecular effectors across a range of concentrations in the brain, eliciting intoxication through to sedation. Invertebrate models including the nematode worm Caenorhabditis elegans have been deployed for molecular genetic studies to inform on key components...

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Detalhes bibliográficos
Main Authors: Dillon, James, Andrianakis, Ioannis, Mould, Richard, Ient, Ben, Liu, Wei, James, Christopher, O'Connor, Vincent, Holden-Dye, Lindy
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046189/
https://ncbi.nlm.nih.gov/pubmed/23882127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-189340
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