A Differential Role for Neuropeptides in Acute and Chronic Adaptive Responses to Alcohol: Behavioural and Genetic Analysis in Caenorhabditis elegans

Prolonged alcohol consumption in humans followed by abstinence precipitates a withdrawal syndrome consisting of anxiety, agitation and in severe cases, seizures. Withdrawal is relieved by a low dose of alcohol, a negative reinforcement that contributes to alcohol dependency. This phenomenon of ‘with...

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Détails bibliographiques
Auteurs principaux: Mitchell, Philippa, Mould, Richard, Dillon, James, Glautier, Steven, Andrianakis, Ioannis, James, Christopher, Pugh, Amanda, Holden-Dye, Lindy, O'Connor, Vincent
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862703/
https://ncbi.nlm.nih.gov/pubmed/20454655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010422
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