Targeting prostate cancer cell lines with polo-like kinase 1 inhibitors as a single agent and in combination with histone deacetylase inhibitors

Combinations of anticancer therapies with high efficacy and low toxicities are highly sought after. Therefore, we studied the effect of polo-like kinase 1 (Plk1) inhibitors on prostate cancer cells as a single agent and in combination with histone deacetylase (HDAC) inhibitors valproic acid and vori...

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Bibliographic Details
Main Authors: Wissing, Michel D., Mendonca, Janet, Kortenhorst, Madeleine S. Q., Kaelber, Nadine S., Gonzalez, Matthew, Kim, Eunice, Hammers, Hans, van Diest, Paul J., Carducci, Michael A., Kachhap, Sushant K.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2013
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046181/
https://ncbi.nlm.nih.gov/pubmed/23884428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-222893
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