Population pharmacokinetics of mefloquine, administered as a fixed-dose combination of artesunate-mefloquine in Indian patients for the treatment of acute uncomplicated Plasmodium falciparum malaria

BACKGROUND: Fixed-dose combinations of artemisinin combination therapy are strongly recommended to facilitate drug administration and compliance. New fixed-dose combinations must nevertheless be evaluated in relevant populations in terms of efficacy and pharmacokinetics. METHODS: A single-arm, open-...

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Autors principals: Jullien, Vincent, Valecha, Neena, Srivastava, Bina, Sharma, Bhawna, Kiechel, Jean-René
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046089/
https://ncbi.nlm.nih.gov/pubmed/24886117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-187
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